Polynucleotides are natural compounds that are used in medical and aesthetic treatments to regenerate skin and tissues. They are made up of nucleotide monomers that are covalently bonded in a chain. DNA and RNA are examples of polynucleotides, with DNA consisting of two chains of polynucleotides.  

In aesthetic medicine, polynucleotides are often derived from salmon DNA because they are compatible with human skin and have strong hydrating and tissue-regenerating effects. They work by interacting with skin cells, stimulating their proliferation and encouraging the production of collagen and elastin.  

Polynucleotides can be used for a variety of skin concerns, including:

• Acne

• Atrophic scarring

• Rosacea

• Elastosis

• Alopecia/hair loss

• Hyperpigmentation

• Stretch marks

• Deep lines and wrinkles  

Polynucleotide treatments are administered by registered medical professionals. While results are not immediate, improvements should be visible within a few days. The longevity of the results can vary from person to person, but most people enjoy smoother, plumper skin for 6 to 12 months before needing another treatment.

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A polynucleotide treatment plan typically involves a series of sessions, spaced 2–4 weeks apart, to achieve the desired results. The number of sessions needed depends on the patient's needs, but usually 2–4 sessions are recommended.  

Here are some other things to know about polynucleotide treatments:  

• Treatment process

  Before the injections, the skin is cleansed and numbed with a local anesthetic cream. The polynucleotide solution is then injected into the targeted areas using a needle or cannula.  

• Treatment areas

  Polynucleotide treatments are often used on the face, targeting areas prone to aging, such as the forehead, cheeks, and around the eyes.  

• Treatment benefits

  Polynucleotide treatments can help reduce the signs of sun damage, regulate melanin cells, and rejuvenate the skin. They can also help reduce inflammation, regulate sebum production, and enhance skin texture.  

• Before treatment

  Before receiving a polynucleotide treatment, you should avoid using active skincare ingredients and chemical peels for a period of time. 

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Aftercare for polynucleotide treatments is important to achieve the best results. Here are some tips for aftercare:  

• Avoid touching: Avoid touching the treated area for at least six hours after treatment.  

• Avoid makeup: Avoid applying makeup to the treated area for at least 24 hours after treatment.  

• Avoid heat: Avoid exposing the treated area to intense heat, such as saunas, steam rooms, hot showers, and sunbathing, for the first three days after treatment.  

• Avoid exercise: Avoid strenuous exercise for at least 24 hours after treatment.  

• Avoid alcohol: Avoid alcohol consumption for at least 24 hours before and after treatment.  

• Use sunscreen: Apply a broad-spectrum sunscreen with an SPF of 30 or higher daily.  

• Use a gentle cleanser: After the first six hours, you can wash the treated area with a gentle cleanser.  

• Use a gentle moisturizer: Use a gentle moisturizer after treatment.  

• Follow up: A follow-up appointment will be scheduled to monitor your progress and ensure optimal healing. 

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Appointments can be made here.